ACCURACY OF THE PC100 FOR WHOLE BLOOD COUNTS
Accuracy is a measure of closeness of the agreement between the quantified analyte values obtained by the tested method/device and the true values of the gold reference method/device. Systematic error or inaccuracy is quantified by the average bias, which is usually expressed as the constant and proportional bias from a regression procedure. Following the CLSI EP9 method comparison guideline, the passing-bablok linear regression method was used to find the best mathematical fit between the quantified platelets obtained by PC100 and the reference device.
There is a close agreement between the quantified platelet values of PC100 and Sysmex® XN-9000 Automated Hematology System. Results of regression analysis showed that the PC100 Platelet Counter can quantify blood platelets with an average bias (inaccuracy) of -3.362 (-2.312%) across the concentration range of 20-600 platelet/nanolitre. Accuracy is thus above 95%.
PRECISION OF the PC100 FOR WHOLE BLOOD COUNTS
Precision is a measure of closeness of agreement between quantified analyte values obtained by repeated measurements of the same sample/object under a specific set of conditions. Random error or imprecision is commonly expressed as the coefficient of variation (CV) calculated from the results of a set of duplicate measurements. Using duplicates for each sample, the CV% was calculated for the platelets of blood samples counted by PC100.
The PC100 Platelet Counter counts platelets with an average precision of 97.5% in the range of 20-600 platelet/nanolitre.
ACCURACY OF THE PC100 FOR PRP COUNTS
There is close agreement between the quantified platelet values of the PC100 Platelet Counter and Sysmex® XP-300 Automated Hematology System. Results of regression analysis showed that the PC100 Platelet Counter can quantify PRP platelets with an average bias (inaccuracy) of (2.0%) across the concentration range of 250-3600 platelet/nanolitre. Accuracy is thus above 95%.
